TrialX
Image

Evaluation of Post Operative Pain in Retreatment of Molars Using Different Irrigant

Evaluation of Post Operative Pain in Retreatment of Molars Using Different Irrigant

Recruiting
15-70 years
All
Phase 1

Overview

This study evaluates the efficacy of dexamethasone as a intracanal irrigant along with sodium hypochlorite 1% and 5.25% concentrations in post treatment pain for molar root canal retreatment.

Description

Main objective of root canal retreatment is to alleviate pain and disinfect the rootcanal .However some patients may experience mild to severe pain following treatment , which leads to intake of painkillers orally for post operative pain management.

So , this study evaluates the efficiency of dexamethasone used as intracanal irrigant in post treatment pain for molar root canal retreatment sodium hypochlorite (1% &5.25%) is used for disinfecting the canals patients will be grouped into Symptomatic and Asymptomatic patients requiring root canal retreatment and irrigants will be used in various combinations as mentioned below

  1. 1% sodium hypochlorite alone 2.5ml in each canal along with ultrasonic activation
  2. 1% sodium hypochlorite and dexamethasone 4mg,2.5ml in each canal along with ultrasonic activation
  3. 5.25% sodium hypochlorite alone 2.5ml in each canal along with ultrasonic activation
  4. 5.25% sodium hypochlorite and dexamethasone 4mg, 2.5ml in each canal along with ultrasonic activation calcium hydroxide is commonly used as intracanal medicament in all the patients post operative symptoms is evaluated at 12 hrs , 24 hrs,48 hrs, 72 hrs and 1 week followed by obturation is completed

Eligibility

Inclusion Criteria:

  • teeth previously treated or attempted root canal treatment,
  • teeth with or without symptoms,
  • periapical radiograph showing evidence of inadequate previous root canal treatment or periapical changes,
  • only teeth or at least one canal where complete removal of root canal filling material was possible and reach the working length in first appointment.

Exclusion Criteria:

  • patient not willing for follow up,
  • teeth with extensive cervical or apical resorption that restricted the use of sodium hypochlorite irrigation,
  • teeth with poor periodontal status, teeth not suitable for post endodontic restoration,
  • patients with acute periapical abscess,
  • patients with systemic conditions preventing radiograph exposure or multi visit treatment,
  • pregnant patients,
  • patients with allergy to any known dental materials.

Study details
    Root Canal Infection

NCT04250519

Tamil Nadu Dr.M.G.R.Medical University

16 February 2024

Step 1 Get in touch with the nearest study center
Message sent successfully.
We have submitted the information you provided to the research team at the location you chose. For your records, we have sent a copy of the message to your email address.
If you would like to be informed of other studies that may be of interest to you, you may sign up for Patient Notification Service.
Sign up

Send a message

Enter your contact details to connect with study team


Email

View email

Phone

Phone country flag

View phone
Investigator Avatar

Primary Contact

First name*
Last name*
Email*
Phone number*
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.