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The Impact of Gut Microbiota in Anastomoses Insufficiency After Resection and Direct Anastomosis for Colorectal Cancer.

The Impact of Gut Microbiota in Anastomoses Insufficiency After Resection and Direct Anastomosis for Colorectal Cancer.

Recruiting
18 years and older
All
Phase N/A

Overview

The role of gut microbiota in anastomosis insufficiency in patients operated for colorectal cancer and for peritoneal carcinomatosis is going to be investigated. This is a pilot study.

Eligibility

Inclusion Criteria Colorectal group

  • adenocarcinom in colon or rektum
  • curative operation planed
  • direct anastomose plan
  • elective surgery

Inclusion Criteria HIPEC group :

  • All patients with appendix, colon or rectal cancer accepted for CRS+HIPEC

Exclusion Criteria:

  • Ongoing antibiotics treatment
  • antibiotics treatment in the last 6 months
  • acute surgery
  • palliative surgery
  • Ulcers colitis or Crohns disease
  • Prior colectomy
  • Small intestine stoma before the operation
  • neoadjuvant treatment
  • Colon preparation

Study details
    Colorectal Cancer
    Peritoneal Carcinomatosis
    Anastomosis Insufficiency

NCT04252560

Uppsala University Hospital

16 February 2024

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