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Is SPGB Have an Effect on ICP and Oxygenation of Cerebral Venous Outflow in Craniotomy for Cerebral Tumors?

Is SPGB Have an Effect on ICP and Oxygenation of Cerebral Venous Outflow in Craniotomy for Cerebral Tumors?

Recruiting
18-70 years
All
Phase N/A

Overview

This study aims to investigate the effect of Sphenopalatine Ganglion Block on ICP and arterio- jugular venous oxygen difference (AJVDO2) and jugular bulb oxygen saturation (SjVO2). Throughout this study, the efficacy of Sphenopalatine Ganglion Block as scalp block in craniotomy operation will be assessed, and the effect of SPGB on cerebral hemostasis during craniotomy will be evaluated by monitoring of both ICP, AJVDO2 and SjVO2.

Description

This study was performed in the Neurosurgical operating room and included 20 patients allocated into two groups: the treatment group (block group) and the control group (non-block group). 10 patients enrolled in block group and 10 patients in non-block group.

Intraoperative ICP monitoring by subdural ICP monitors will be done every 20 minutes in both block and non- block groups until craniotomy has been occurred, then at the time of closure of the dura . Arterio- jugular venous oxygen difference and Jugular venous bulb oxygen saturation changes will be recorded every 20 minutes in block and non- block groups throughout time of the surgery.

Eligibility

Inclusion Criteria:

  • Patients who prepared for a neurosurgical intervention for elective supratentorial tumor removal
  • ASA 1 and 2
  • Age above 18 years and below 70 years
  • Fully conscious patients.

Exclusion Criteria:

  • Patients with cardiovascular including hypertensive patients or respiratory diseases
  • Pregnancy
  • Patient refusal

Study details
    Cerebral Tumor

NCT04434651

Zagazig University

5 August 2020

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