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Brain MRI in Stroke Patients With Intracardiac Thrombus

Brain MRI in Stroke Patients With Intracardiac Thrombus

Recruiting
18 years and older
All
Phase N/A

Overview

In earlier reports, infarction of cardioembolic origin has been associated with acute lesions involving the cortex, and with multiple acute lesions in single or multiple cerebral circulation territories, and small (most often chronic and asymptomatic) cortical cerebellar infarctions (SCCI). Our aim was to analyse brain MRI characteristics in patients presenting with acute infarction associated with intracardiac thrombus, and to compare them with stroke patients with atrial fibrillation (AF).

Eligibility

Inclusion Criteria:

  • Consecutive patients, recruited and registered in the stroke database between June 2018 and November 2019 of our center (Nmes University Hospital, France), presenting with acute symptomatic infarction (confirmed by diffusion-weighted MRI) associated with intracardiac thrombus or with with known or newly discovered AF
  • Patients with MRI as part of their diagnostic work-up within one week after symptom onset (including diffusion-weighted imaging, intra- [TOF, gadolinium-enhanced MRA, and/or CTA] and extracranial [gadolinium-enhanced MRA, CTA, and/or duplex ultrasound] vessel imaging, contrast transoesophageal or contrast transthoracic echocardiography, and 24h ECG monitoring (acute stroke unit monitoring and/or Holter monitoring)

Exclusion Criteria:

  • opt-out patient

Study details
    Cerebrovascular accident
    Intracardiac Thrombus

NCT04456309

Centre Hospitalier Universitaire de Nīmes

16 February 2024

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